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Identification of serotype 9 human rotavirus by enzyme-linked immunosorbent assay with monoclonal antibodies

Year: 1989

Type: article

Abstract: Hybridomas producing monoclonal antibodies to VP7, a major neutralizing protein of serotype 9 rotavirus (strain W161), were prepared. One monoclonal antibody, W161-6A1, was shown to neutralize only serotype 9 rotavirus strains and reacted specifically with serotype 9 rotaviruses in an enzyme-linked immunosorbent assay. The development of an immunoassay for detection of serotype 9 rotaviruses should facilitate epidemiologic studies.

Source: Journal of Clinical Microbiology

DOI: 10.1128/jcm.27.9.2112-2114.1989

Authors: K Midthun, J Valdesuso, A Z Kapikian, Y Hoshino, K Y Green

Institution: National Institutes of Health

Language: English

Topic: Viral gastroenteritis research and epidemiology

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W1730531114

FWCI: 1.118

Cites: 18

Cited by: 15

Related to: 10