The emerging therapeutic role of probiotics in inflammatory bowel disease.
Year: 2008
Type: article
Abstract: Nonpathogenic bacteria in a genetically susceptible individual play a suggestive role in the pathogenesis of inflammatory bowel disease (IBD). Probiotics are living organisms that exert a protective effect on intestinal mucosa. Although evidence supporting their use for inducing or maintaining remission of IBD remains limited, it may be reasonable to use probiotics as an adjunct to standard therapy for mild-to-moderate disease. Genetically modified probiotics may provide novel delivery methods of therapeutic payloads to inflamed intestinal mucosa. This review focuses on the emerging use of probiotics in the treatment of IBD.
Source: Europe PMC (PubMed Central)
Authors: Matthew Chandler, Eric Wollins, Anastasia Toles, Marie Borum, David B Doman
Institution: George Washington University
Language: English
Subfield: Food Science
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W173405603