Work

The anticancer prodrug CPT-11 is a potent inhibitor of acetylcholinesterase but is rapidly catalyzed to SN-38 by butyrylcholinesterase.

Year: 1999

Type: article

Source: PubMed

Authors: C L Morton, R M Wadkins, M K Danks, P M Potter

Institution: St. Jude Children's Research Hospital

Language: English

Topic: Cholinesterase and Neurodegenerative Diseases

Subfield: Pharmacology (medical)

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funder: National Cancer Institute

Awards: MODULATION OF RHABDOMYOSARCOMA PHENOTYPE, SELECTIVE THERAPY OF TUMORS THAT OVEREXPRESS C MYC, Cancer Center Support Grant (CCSG)

OpenAlex ID: W1742031210

FWCI: 3.525

Cites: 28

Cited by: 91

Related to: 10