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In vivo genome editing using nuclease-encoding mRNA corrects SP-B deficiency

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Year: 2015
Type: article
Source: Nature Biotechnology
DOI: 10.1038/nbt.3241
Authors: Azita J Mahiny, Alexander Dewerth, Lauren E Mays, Mohammed Alkhaled, Benedikt Mothes, Emad Malaeksefat, Brigitta Loretz, Jennifer Rottenberger, Darina M Brosch, Philipp Reautschnig, Pacharapan Surapolchai, Franziska Zeyer, Andrea Schams, Melanie Carevic, Martina Bakele, Matthias Griese, Matthias Schwab, Bernd Nürnberg, Sandra Beer-Hammer, Rupert Handgretinger, Dominik Hartl, Claus-Michael Lehr, Michael S D Kormann
Institutions: University of Tübingen, Helmholtz Centre for Infection Research, Helmholtz Institute for Pharmaceutical Research Saarland, German Center for Lung Research, Ludwig-Maximilians-Universität München, Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Saarland University
Language: English

Topic: CRISPR and Genetic Engineering
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: European Respiratory Society, Deutsche Forschungsgemeinschaft
Awards: G274250440, G6984477434
OpenAlex ID: W1750553863
FWCI: 6.922
Cites: 18
Cited by: 141
Related to: 10
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