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Brief Report

Year: 2015
Type: article
Study design: Observational Study
Abstract: Malawi adopted the Option B+ strategy in 2011. Its success in reducing mother-to-child transmission depends on coverage and timing of HIV testing. We assessed HIV status ascertainment and its predictors during pregnancy. HIV status ascertainment was 82.3% (95% confidence interval: 80.2 to 85.9) in the pre-Option B+ period and 85.7% (95% confidence interval: 83.4 to 88.0) in the Option B+ period. Higher HIV ascertainment was independently associated with higher age, attending antenatal care more than once, and registration in 2010. The observed high variability of HIV ascertainment between sites (50.6%-97.7%) and over time suggests that HIV test kit shortages and insufficient numbers of staff posed major barriers to reducing mother-to-child transmission.
DOI: 10.1097/qai.0000000000000669
Authors: Lyson Tenthani, Andreas D. Haas, Matthias Egger, Joep J van Oosterhout, Andreas Jahn, Frank Chimbwandira, Kali Tal, Landon Myer, Janne Estill, Olivia Keiser
Institutions: University of Bern, University of Malawi, University of Cape Town, University of Washington, Dignitas International, Ministry of Health, Malawi Government
Language: English
Field: Medicine
Open Access status: green
Funders: National Science Foundation, United States Agency for International Development, Bill and Melinda Gates Foundation, Global Fund to Fight AIDS, Tuberculosis and Malaria, U.S. President’s Emergency Plan for AIDS Relief, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, National Institutes of Health, National Institute of Allergy and Infectious Diseases
Awards: G1002764156, G1126150394, G1651421172, G596821015, COOPERTIVE AGREEMENT, Mathematical simulation models to test the impact and cost-effectiveness of health interventions – applications in HIV, tuberculosis, cancer and hepatitis C
OpenAlex ID: W1751991607
FWCI: 2.165
Cites: 10
Cited by: 28
Related to: 10