Work

Small-Molecule Reactivation of Mutant p53 to Wild-Type-like p53 through the p53-Hsp40 Regulatory Axis

Year: 2015

Type: article

Source: Chemistry & Biology

DOI: 10.1016/j.chembiol.2015.07.016

Authors: Masatsugu Hiraki, So-Young Hwang, Shugeng Cao, Timothy R. Ramadhar, Sanguine Byun, Kyoung Wan Yoon, Jung Hyun Lee, Kiki Chu, Aditi U. Gurkar, Vihren Kolev, Jianming Zhang, Takushi Namba, Maureen E. Murphy, David J. Newman, Anna Mandinova, Jon Clardy, Sam W. Lee

Institutions: Harvard University, Massachusetts General Hospital, University of Hawaii at Hilo, The Wistar Institute, Frederick National Laboratory for Cancer Research, Broad Institute, Massachusetts Institute of Technology

Language: English

Topic: Cancer-related Molecular Pathways

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Harvard University, National Institutes of Health, Japan Society for the Promotion of Science, National Cancer Institute, National Institute of General Medical Sciences, FAS Division of Science, Harvard University

Awards: G2684484640, G2699332470, Targeted Therapies in Melanoma, G3021990561, G351856440, G3997013738, Analysis of p53 new function for protein synthesis and identification of new anti-cancer target, G4870014862, p53-GAMT pathway in cancer cell metabolism and DNA damage-induced carcinogenesis, HSP70 and melanoma, p53 - Regulators and Effectors, G7733477404, Chemical biology of bacterial symbionts, G9000056139, G9000097847, G9000195373, Consolidated Basic Cancer Research Program, G90327178

OpenAlex ID: W1763368382

FWCI: 3.122

Cites: 51

Cited by: 81

Related to: 10