Estudo Da Imunolocalização De Miosina V Em Tumores De Glângulas Salivares E Epidermóides Bucais
Year: 2009
Type: article
Abstract: The programmed cell suicide, the apoptosis, is crucial for the survival and balance of any living organism. The cancer is characterized by disordered growth of cells that survive the control apoptosis, resulting from the accumulation of genetic alterations or epigenetic somatic tissue from a previously healthy. Some studies have linked the protein, myosin-Va and DLC1, participating in the cascade of molecular events that promote apoptosis. The goal is being investigated methods imunocitquimicos for the detection and localization of these proteins in oral cell carcinomas and salivary glands of patients the HC-UFU. The procedures for collecting, processing and analysis of the samples were adjusted and standardized. The partial results show need to improve the method of immunodetection for myosin-Va and show that this protein is found in the endothelium of five samples of tumors. She graduated from a bank kept fresh in ultrafreezer tumors (7 of 25, epidermal glands and oral) for the continuation of this study, aiming to clarify the expression and localization of both proteins with characteristics of tumors and pathological records of patients.
Language: Portuguese
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W1766648039