Analysis of lymphopoietic stem cells with a monoclonal antibody to the rat transferrin receptor.
Year: 1985
Type: article
Abstract: A mouse monoclonal IgG2a antibody, designated MRC OX-26, is shown to be specific for the rat transferrin receptor, but does not block transferrin binding. The antibody labelled a myeloma, three leukaemia cell lines and normal dividing cells of various types, but also bound to a number of nondividing normal tissues. No labelling of lymphopoietic stem cells could be detected, even though approximately 25% of bone marrow and over 95% of fetal liver cells were clearly labelled.
Source: PubMed Central
Authors: W A Jefferies, M R Brandon, A F Williams, S V Hunt
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W176676541