Clinical relevance of DPYD variants c.1679T>G, c.1236G>A/HapB3, and c.1601G>A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data
Year: 2015
Type: review
Study designs: Systematic Review, Meta-Analysis
Source: The Lancet Oncology
Authors: Didier Meulendijks, Linda M Henricks, Gabe S Sonke, Maarten J Deenen, Tanja K Froehlich, Ursula Amstutz, Carlo R Largiadèr, Barbara A Jennings, Anthony M Marinaki, Jeremy D Sanderson, Zdenek Kleibl, Petra Kleiblova, Matthias Schwab, Ulrich M Zanger, Claire Palles, Ian Tomlinson, Eva Gross, André B P van Kuilenburg, Cornelis J A Punt, Miriam Koopman, Jos H Beijnen, Annemieke Cats, Jan H M Schellens
Institutions: The Netherlands Cancer Institute, University of Bern, University Hospital of Bern, University of East Anglia, St Thomas' Hospital, Charles University, Universitätsklinikum Tübingen, Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, University of Tübingen, Centre for Human Genetics, University of Oxford, Technical University of Munich, Amsterdam UMC Location University of Amsterdam, University of Amsterdam, University Medical Center Utrecht, Utrecht University
Language: English
Subfield: Pharmacology
Domain: Life Sciences
Open Access status: bronze
Funder: Cancer Research UK
Award: G3097030853
OpenAlex ID: W1774948393