Work

SBEAMS-Microarray: database software supporting genomic expression analyses for systems biology

Year: 2006

Type: article

Abstract: BACKGROUND: The biological information in genomic expression data can be understood, and computationally extracted, in the context of systems of interacting molecules. The automation of this information extraction requires high throughput management and analysis of genomic expression data, and integration of these data with other data types. RESULTS: SBEAMS-Microarray, a module of the open-source Systems Biology Experiment Analysis Management System (SBEAMS), enables MIAME-compliant storage, management, analysis, and integration of high-throughput genomic expression data. It is interoperable with the Cytoscape network integration, visualization, analysis, and modeling software platform. CONCLUSION: SBEAMS-Microarray provides end-to-end support for genomic expression analyses for network-based systems biology research.

Source: BMC Bioinformatics

DOI: 10.1186/1471-2105-7-286

Authors: Bruz Marzolf, Eric W Deutsch, Patrick Moss, David Campbell, Michael H Johnson, Timothy Galitski

Institution: Institute for Systems Biology

Language: English

Topic: Bioinformatics and Genomic Networks

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $2,990

Funders: National Institutes of Health, National Institute of General Medical Sciences