Work

The Role of Radiation Therapy in the Treatment of Medullary Thyroid Cancer

Year: 2010

Type: article

Abstract: Medullary thyroid cancer (MTC) is a neuroendocrine tumor derived from parafollicular or C cells of the thyroid gland. Surgical resection is the mainstay of treatment for MTC. External-beam radiation treatment (EBRT) has traditionally played a limited role in the management of MTC. Despite aggressive surgery, patients at high risk for local recurrence may benefit from adjuvant EBRT. With improvements in radiation technique, adequate dose can be effectively delivered to the region at risk while minimizing dose to surrounding critical structures. Although the role of EBRT in the management of these tumors has thus far been poorly defined, EBRT should be considered as a treatment option for patients with locally advanced MTC to optimize locoregional control.

Source: Journal of the National Comprehensive Cancer Network

DOI: 10.6004/jnccn.2010.0041

Authors: Stephanie A. Terezakis, Nancy Y. Lee

Institutions: Johns Hopkins University, Johns Hopkins Medicine, Memorial Sloan Kettering Cancer Center

Language: English

Topic: Thyroid Cancer Diagnosis and Treatment

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W1790536745