Year: 2007
Type: article
Abstract: HCV infection usually presents as an acute infection, chronic infection or as an extrahepatic manifestation.Acute infection is rarely recognized in clinical practice beceause the large majority of the patients are asimptomatic or develop symptoms which don't attract clinical attention such as sickness, anorexy, anxiety and pain in the upper right quadrant of stomach, mialgy and artralgy.Therefore, chronic hepatitis is diagnosed in a large majority of the patients after many years in case of large values of aminotransferasis during a routine laboratory check.A vast number of diseases are directly or indirectly connected with chronic hepatitis C. It is known for some of the extrahepatic manifestations to be firmly connected with hepatitis C while there is a doubt for others.Chronic hepatitis C is disease with no symptoms manifested for a long time or the symptoms are uncharacteristic, so it often becomes visible after development end-stage liver disease.It is considered that around 20% of the patients with the chronic type of the disease will develop cirrhosis within a period of 10 -30 years with the possibility of developing hepatocellular carcinoma in 1% -5% of the cases per year.Furthemore, decompensation of liver cirrhosis and hepatocellular carcinoma are the leading indications for liver transplantation in patients with chronic hepatitis C. Key words: acute infection, chronic infection
Authors: Sandra Milić, Ivana Mikolašević
Institutions: Klinički Bolnički Centar Rijeka, University of Rijeka
Language: English
Topic: Hepatitis C virus research
Subfield: Hepatology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W1204613821