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Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation

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Year: 2015
Type: article
Source: Cell Death and Differentiation
DOI: 10.1038/cdd.2015.93
Authors: M Hayano, W S Yang, C K Corn, N C Pagano, B R Stockwell
Institutions: Columbia University, Howard Hughes Medical Institute
Language: English

Topic: Ferroptosis and cancer prognosis
Subfield: Cancer Research
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: bronze

Funders: Howard Hughes Medical Institute, New York State Stem Cell Science, National Institutes of Health, National Cancer Institute, National Institute of General Medical Sciences
Awards: Defining the functions and translational potential of ferroptosis, Defining a novel trigger for apoptosis, G1920950160, Roles and Regulation of wild-type and mutant forms of p53, G3209517190, Chemical genetic profiling of engineered tumor cells, G3914737044, Comparing HTS with Fragment-Based Design for B-Raf and the Ras-Raf Interaction, Cancer Biology Training Grant, Cancer Center Support Grant
OpenAlex ID: W1798710600
FWCI: 4.439
Cites: 25
Cited by: 470
Related to: 10
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