Work

Studies on the prophylactic and radical curative activity of RC-12 against Plasmodium cynomolgi in Macaca mulatta.

Year: 1972

Type: article

Abstract: The compound 4-(2-bromo-4,5-dimethoxyphenyl)-1,1,7,7-tetraethyldiethylenetriamine (RC-12) has been shown to be active against the exoerythrocytic (EE) stages of the malaria parasite. Experiments on Plasmodium cynomolgi in rhesus monkeys showed that single weekly doses of 25 mg per kg of body weight would prevent the development and/or maturation of EE stages. The usefulness of RC-12 for effecting radical cures is, however, still open to doubt.

Source: Europe PMC (PubMed Central)

Authors: T M Sodeman, P G Contacos, W E Collins, C S Smith, J R Jumper

Language: English

Topic: Malaria Research and Control

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W1806764603

FWCI: 3.852

Cites: 1

Cited by: 10

Related to: 10