Work

Duck hepatitis B virus (DHBV) particles produced by transient expression of DHBV DNA in a human hepatoma cell line are infectious in vitro

Year: 1988

Type: article

Abstract: Transfection of the human hepatocellular carcinoma cell line HuH7 with a plasmid containing a tandem copy of the duck hepatitis B virus DNA sequence resulted in transient replication of the virus. Viral particles secreted by transfected HuH7 cells exhibited physical properties similar to those of serum-derived duck hepatitis B virus and were infectious in primary duck hepatocyte cultures.

Source: Journal of Virology

DOI: 10.1128/jvi.62.9.3513-3516.1988

Authors: J C Pugh, K Yaginuma, K Koike, J Summers

Institution: Fox Chase Cancer Center

Language: English

Topic: Hepatitis B Virus Studies

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Cancer Institute, National Center for Research Resources