Work

Thermoresponsive release of viable microfiltrated Circulating Tumor Cells (CTCs) for precision medicine applications

Year: 2015

Type: article

Abstract: Stimulus responsive release of Circulating Tumor Cells (CTCs), with high recovery rates from their capture platform, is highly desirable for off-chip analyses. Here, we present a temperature responsive polymer coating method to achieve both release as well as culture of viable CTCs captured from patient blood samples.

Source: Lab on a Chip

DOI: 10.1039/c5lc01024a

Authors: Zheng Ao, Erika Parasido, Siddarth Rawal, Anthony Williams, Richard Schlegel, Stephen Liu, Chris Albanese, Richard J. Cote, Ashutosh Agarwal, Ram H. Datar

Institutions: University of Miami, Georgetown University Medical Center, Georgetown Lombardi Comprehensive Cancer Center

Language: English

Topic: Microfluidic and Bio-sensing Technologies

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases, National Center for Advancing Translational Sciences, Medical Research and Materiel Command

Awards: G11184930, G1522865146, G2179035730, Integrated Microdevice to Capture and Detect Circulating Tumor Cells, Circulating Tumor Cell Capture & Analysis in a Multi-Center Prostate Cancer Trial, G3786209556, G4932495280, Engineering a Human Physiomimetic Islet Microsystem, G6081897200, Culturing viably captured circulating tumor cells using conditional reprogramming, G667479965, G7652619886, G7832085018, G8588691394, G9000076464, G9000255761, Georgetown University Lombardi Comprehensive Cancer Center Support Grant

OpenAlex ID: W1812949703

FWCI: 1.574

Cites: 24

Cited by: 29

Related to: 10