Work

Synthesis of 6-bromo-4-iodoquinoline

Year: 2015

Type: conference-paper

Abstract: Bromo-4-iodoquinoline is an important intermediate for the synthesis of many biologically active compounds, such as GSK2126458.It was synthesized from 2,2-dimethyl-1,3dioxane-4,6-dione and 4-bromoaniline through five steps including cyclization reaction and substitution reaction.And the structures of 6-bromoquinolin-4-ol and 6-bromo-4-iodoquinoline were confirmed by 1 H NMR spectrum.

Source: Advances in engineering research/Advances in Engineering Research

DOI: 10.2991/asei-15.2015.424

Authors: Wenhui Wang, Yuping Guo, Linxiao Wang, Yiqiang OuYang, Qinqin Wang, Wufu Zhu

Institution: Jiangxi Science and Technology Normal University

Language: English

Topic: Synthesis and Reactivity of Heterocycles

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Funder: Natural Science Foundation of Jiangxi Province

Award: G973567506