A critical view on neuronal polarization: How to make a single axon?
Year: 2009
Type: dissertation
Abstract: During neuronal development, one axon and several dendrites are formed out of the immature neurites of one \nsingle neuron. The asymmetrical structure allows neurons to receive (dendrites) and transmit (axon) signals. A lot \nof molecules are implicated to play a role in neuronal polarization. This thesis touches on the molecules and the \ncellular mechanisms that contribute to the polarization of neurons. Most of these molecules act on the actin or \nmicrotubule cytoskeleton. Most likely, neuronal polarization is initiated or stimulated by the cooperative action of \nactin and microtubules regulatory proteins. Suggestions for research that should clarify the process further, \ninvolve in vivo research.
Author: Sanne Moorman
Language: English
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W182640996