Work

Functional and ultrastructural changes in alveolar macrophages from rabbits colonized with Bordetella bronchiseptica

Year: 1986

Type: article

Abstract: Alveolar macrophages from rabbits colonized with Bordetella bronchiseptica in their respiratory tract exhibited significant decreases in cell adherence, phagocytic uptake, and bactericidal activity compared with macrophages from uncolonized animals. These dysfunctions were accompanied by ultrastructural changes, including a decrease in overall cell density, a vacuolation of the rough endoplasmic reticulum, and an increase in organelle-poor cell surface projections.

Source: Infection and Immunity

DOI: 10.1128/iai.53.3.702-706.1986

Authors: B J Zeligs, J D Zeligs, J A Bellanti

Language: English

Topic: Bacterial Infections and Vaccines

Subfield: Microbiology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Heart, Lung, and Blood Institute, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Awards: G1649555515, G6331805924, PHAGOCYTIC CELL FUNCTION IN NEWBORN &DEVELOPING INFANT