Work

Posttranscriptional effector domains in the Rev proteins of feline immunodeficiency virus and equine infectious anemia virus

Year: 1994

Type: article

Abstract: By systematically dissecting the Rev proteins of feline immunodeficiency virus (FIV) and equine infectious anemia virus (EIAV), we have identified within each a short peptide that is functionally interchangeable with the effector domains found in Rev-like proteins from other retroviruses. The active sequences from FIV and EIAV differ in several respects from other known effectors and may represent a distinct class of effector domain.

Source: Journal of Virology

DOI: 10.1128/jvi.68.3.1998-2001.1994

Authors: V A Mancuso, T J Hope, L Zhu, D Derse, T Phillips, T G Parslow

Institutions: University of California, San Francisco, Salk Institute for Biological Studies

Language: English

Topic: HIV Research and Treatment

Subfield: Virology

Field: Immunology and Microbiology

Domain: Life Sciences

Open Access status: green

Funders: National Institutes of Health, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases

Awards: FUNCTION AND INHIBITION OF THE REV GENE PRODUCT OF HIV, REGULATORY ELEMENTS IN THE IMMUNOGLOBULIN KAPPA GENES, G5258276880, G6162319956