Work

Identification of the Cloned Gene for the Murine Transplantation Antigen H-2Kb by Hybridization with Synthetic Oligonucleotides

Year: 1983

Type: article

Abstract: The H-2K(b) gene is a member of the large major histocompatibility complex class I gene family. Since many members of this family cross-hybridize with class I cDNA probes, the cloned H-2K(b) gene was identified by hybridization with specific oligonucleotide probes. This clone was definitively shown to encode the H-2K(b) polypeptide by partial DNA sequencing and by serological and tryptic peptide analyses of the expressed product.

Source: Molecular and Cellular Biology

DOI: 10.1128/mcb.3.4.750

Authors: Dan H. Schulze, Larry R. Pease, Yuichi Obata, Stanley G. Nathenson, Antonio A. Reyes, Satoshi Ikuta, R. Bruce Wallace

Institutions: Albert Einstein College of Medicine, Memorial Sloan Kettering Cancer Center, City Of Hope National Medical Center, City of Hope

Language: English

Topic: vaccines and immunoinformatics approaches

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W1840106782

FWCI: 1.853

Cites: 22

Cited by: 38

Related to: 10