Year: 2015
Type: review
Abstract: Individual participant data (IPD) meta-analysis is an increasingly used approach for synthesizing and investigating treatment effect estimates. Over the past few years, numerous methods for conducting an IPD meta-analysis (IPD-MA) have been proposed, often making different assumptions and modeling choices while addressing a similar research question. We conducted a literature review to provide an overview of methods for performing an IPD-MA using evidence from clinical trials or non-randomized studies when investigating treatment efficacy. With this review, we aim to assist researchers in choosing the appropriate methods and provide recommendations on their implementation when planning and conducting an IPD-MA.
Source: Research Synthesis Methods
DOI: 10.1002/jrsm.1160
Authors: Thomas P. A. Debray, Karel G. M. Moons, Gert van Valkenhoef, Orestis Efthimiou, Noemi Hummel, Rolf H. H. Groenwold, Johannes B. Reitsma, on behalf of the GetReal methods review group
Language: English
Subfield: Statistics, Probability and Uncertainty
Field: Decision Sciences
Domain: Social Sciences
Open Access status: hybrid
Estimated APC paid: $3,020
OpenAlex ID: W1841651683