Hormone replacement therapy: a time for pause.
Year: 2002
Type: article
Abstract: Oh, what a tangled web we weave, When first we practice to deceive! — Sir Walter Scott, Marmion Apill that prevents the ills of aging — fewer heart at-tacks, stronger bones and better quality of life —how can women be denied this wonder pill? Thus, some physicians have been prescribing various hormone preparations (estrogens with or without progestins) since the mid-1970s, and women in Western societies have been willingly taking them. Some “minor ” side effects were known — clots in the legs and gallstones — but most be-lieved that the benefits outweighed the inconveniences. All this has to be rethought with the early termination of one of the trial arms of the Women’s Health Initiative (WHI) that was evaluating hormone replacement therapy (HRT).1 Menopause heralds the end of reproductive life for women, but why most species continue to have reproduc-
Source: Europe PMC (PubMed Central)
Authors: Salim Yusuf, Sonia Anand
Institutions: Heart and Stroke Foundation, McMaster University
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W1842888759