Work

Latent herpes simplex virus type 1 gene expression in ganglia innervating the human gastrointestinal tract

Year: 1997

Type: article

Abstract: Using in situ hybridization, we demonstrated that latent herpes simplex virus type 1 (HSV-1) gene expression is prevalent in human adult nodose ganglia. This suggests that infection of gastrointestinal sensory nerves, probably through swallowed virus-laden oral secretions, occurs commonly and that HSV-1 reactivating from this site may play a role in recurrent gastrointestinal disorders.

Source: Journal of Virology

DOI: 10.1128/jvi.71.5.4103-4106.1997

Authors: R M Gesser, S C Koo

Institution: Children's Hospital of Philadelphia

Language: English

Topic: Herpesvirus Infections and Treatments

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of Allergy and Infectious Diseases