Work

Prenatal-postnatal correlations of brain abnormalities: How lesions and diagnoses change over time

Year: 2015

Type: article

Abstract: A combination of prenatal ultrasound and MRI can be used to detect and characterize many primary and secondary CNS abnormalities in the developing fetus. While this information is useful in prenatal patient counseling, it is important to understand the factors that can influence change in diagnosis and prognosis over time. The etiology of the abnormality, the conspicuity of associated findings, the change in appearance over time, and the opinion of subspecialty experts all can influence the diagnosis. Additionally, technical factors of imaging acquisition may allow the detection of an abnormality in the postnatal period and not prenatally. Having an understanding of the normal fetal central nervous system anatomy at varying gestational ages will aid in the imaging detection and interpretation of CNS pathology. Understanding how these appearances and diagnoses can change over time will aid in the discussion of prognosis with expectant parents, which is crucial in fetal CNS abnormalities.

Source: Journal of Pediatric Neuroradiology

DOI: 10.3233/pnr-2012-027

Authors: Gunjan Senapati, Deborah Levine

Institution: Beth Israel Deaconess Medical Center

Language: English

Topic: Fetal and Pediatric Neurological Disorders

Subfield: Pediatrics, Perinatology and Child Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of Biomedical Imaging and Bioengineering