Work

Quantification of Nigella Sativa Oil (nso) From Biodegradable Plga Nanoparticles Using Ftir Spectroscopy

Year: 2014

Type: article

Abstract: Objective: Quantification of medicinal plant, N. sativa oil, in biodegradable nanoparticles fabricated from PLGA and chitosan was impossible due to the difficulty in the oil extraction-partition method of which the nanoparticle did not dissolve in any solvent. Methods: FTIR method was developed to quantify the loading efficiency of NSO from the intact nanoparticles without the need to solubilise the nanoparticles and extract the NSO thereafter. Beer-Lambert law was applied in the quantification following selection of a few wave number combinations. Results: The method exhibited linearity in the range NSO/PLGA=5-150% with R

Source: International Journal of Pharmacy and Pharmaceutical Sciences

Authors: Abd Almonem Doolaanea, Ahmad Fahmi Harun, Farahidah Mohamed

Institution: International Islamic University Malaysia

Language: English

Topic: Analytical Methods in Pharmaceuticals

Subfield: Analytical Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

OpenAlex ID: W1853984493

FWCI: 0.198

Cites: 28

Cited by: 8

Related to: 10