Work

The combined incremental prognostic value of left ventricular ejection fraction, late gadolinium enhancement and global circumferential strain assessed by cardiovascular magnetic resonance

Year: 2015

Type: article

Abstract: Background Left ventricular ejection fraction (LVEF) is powerful predictor of mortality and is used to guide treatment decisions. It is however subject to limitations, particularly when measured using echocardiography, as is most commonly done. Additionally, many major cardiovascular events occur in patients typically adjudged to be at lower risk using echocardiography (LVEF >35%). Assessment of myocardial deformation (strain) using tagging has the potential to overcome some of the limitations of LVEF. The value of global circumferential strain (GCS) measured by CMR tagging in patients with suspected cardiac disease has not been fully explored despite it being considered as the non-invasive gold standard method of assessment of LV deformation. We aimed to assess the incremental prognostic value of GCS measured using tagging for the prediction of major adverse cardiovascular events in addition to baseline clinical characteristics, LVEF and late gadolinium enhancement (LGE) in an unselected cohort of patients.

Source: Journal of Cardiovascular Magnetic Resonance

DOI: 10.1186/1532-429x-17-s1-q50

Authors: Ify Mordi, Hiram Bezerra, David Carrick, Nikolaos Tzemos

Institutions: University of Glasgow, University Hospitals Cleveland Medical Center, Case Western Reserve University

Language: English

Topic: Cardiovascular Function and Risk Factors

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,000