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Effectiveness of BCG vaccination against tuberculous meningitis: a case-control study in São Paulo, Brazil.

Year: 1990

Type: article

Abstract: A case-control study was carried out in the Metropolitan Region of São Paulo, Brazil, to determine the protection against tuberculous meningitis conferred by BCG vaccination to children aged less than 5 years. The BCG vaccination coverage in the study area was about 88%. A total of 72 tuberculous meningitis patients were studied as well as 505 neighbourhood and 81 hospital controls. Analysis of the data using a conditional logistic regression for matched case-control studies indicated that the efficacy of BCG was similar for both groups of controls, that for neighbourhood controls (84.5%) being slightly greater than that for hospital controls (80.2%). No significant interactions were found between vaccination status and sex, age, or socioeconomic status.

Source: Europe PMC (PubMed Central)

Authors: V Wünsch Filho, E A de Castilho, L C Rodrigues, S R Huttly

Institution: Universidade de São Paulo

Language: English

Topic: Infectious Diseases and Tuberculosis

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W1865364798

FWCI: 3.471

Cites: 7

Cited by: 68

Related to: 10