Work

Evolutionary analyses of HIV-1 protein-coding sequences : adaptation to host cytotoxic immune responses and purifying selection at synonymous sites

Year: 2009

Type: dissertation

Abstract: This thesis exposes previously ignored evolutionary characteristics of the synonymous sites of virus nucleotide sequences and contributes new findings to the understanding of the evolution of HIV-1 in relation to the human immune response.

Source: Open University of Cape Town (University of Cape Town)

Author: Nobubelo Ngandu

Language: English

Topic: Evolution and Genetic Dynamics

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: National Institutes of Health, Fogarty International Center

Award: G345081726

OpenAlex ID: W1874771495

Cites: 215

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Related to: 10