Work

A biphasic scaffold based on silk and bioactive ceramic with stratified properties for osteochondral tissue regeneration

Year: 2015

Type: article

Abstract: testing showed that different compositions in the two phases of the biphasic scaffold could direct the preferential differentiation of human mesenchymal stem cells towards the chondrogenic or osteogenic lineage. By featuring simple and reproducible fabrication and a well-integrated interface, the biphasic scaffold strategy established in this study circumvented the common problems experienced with integrated scaffold designs and could provide an effective approach for the regeneration of osteochondral tissue.

Source: Journal of Materials Chemistry B

DOI: 10.1039/c5tb00353a

Authors: Jiao Jiao Li, Kyungsook Kim, Seyed-Iman Roohani-Esfahani, Jin Guo, David L. Kaplan, Hala Zreiqat

Institutions: The University of Sydney, Tufts University

Language: English

Topic: Bone Tissue Engineering Materials

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Health and Medical Research Council, National Institute of Biomedical Imaging and Bioengineering