Work

Switchable Release of Entrapped Nanoparticles from Alginate Hydrogels

Year: 2015

Type: article

Abstract: Natural biological processes are intricately controlled by the timing and spatial distribution of various cues. To mimic this precise level of control, the physical sizes of gold nanoparticles are utilized to sterically entrap them in hydrogel materials, where they are subsequently released only in response to ultrasound. These nanoparticles can transport bioactive factors to cells and direct cell behavior on-demand.

Source: Advanced Healthcare Materials

DOI: 10.1002/adhm.201500254

Authors: Cathal J. Kearney, Hadas Skaat, Stephen M. Kennedy, Jennifer Hu, Max Darnell, Theresa M. Raimondo, David J. Mooney

Institutions: Harvard University, Royal College of Surgeons in Ireland, Advanced Materials and BioEngineering Research, Wyss Institute for Biologically Inspired Engineering, University of Rhode Island

Language: English

Topic: Hydrogels: synthesis, properties, applications

Subfield: Molecular Medicine

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: National Institute of General Medical Sciences, National Institute of Dental and Craniofacial Research

Awards: Programming dendritic cells in concert with morphagen delivery for periodontal re, Rhode Island IDeA Network of Biomedical Research Excellence

OpenAlex ID: W1875996132

FWCI: 2.076

Cites: 33

Cited by: 67

Related to: 10