Tea and coffee consumption and risk of esophageal cancer: The European prospective investigation into cancer and nutrition study
Year: 2014
Type: article
Study design: Observational Study
Abstract: Epidemiological data regarding tea and coffee consumption and risk of esophageal cancer (EC) is still inconclusive. We examined the association of tea and coffee consumption with EC risk among 442,143 men and women without cancer at baseline from 9 countries of the European Prospective Investigation into Cancer and Nutrition. Tea and coffee intakes were recorded using country-specific validated dietary questionnaires. Cox regression models were used to analyze the relationships between tea and coffee intake and EC risk. During a mean follow-up of 11.1 years, 339 participants developed EC, of which 142 were esophageal adenocarcinoma (EAC) and 174 were esophageal squamous cell carcinoma (ESCC). In the multivariable models, no significant associations between tea (mostly black tea), and coffee intake and risk of EC, EAC and ESCC were observed. In stratified analyses, among men coffee consumption was inversely related to ESCC (HR for comparison of extreme tertiles 0.42, 95% CI 0.20-0.88; p-trend=0.022), but not among women. In current smokers, a significant and inverse association was observed between ESCC risk and tea (HR 0.46, 95% CI 0.23-0.93; p-trend=0.053) and coffee consumption (HR 0.37, 95% CI 0.19-0.73; p-trend=0.011). However, no statistically significant findings were observed using the continuous variable (per 100 mL/d). These data did not show a significant association between tea and coffee consumption and EC, EAC and ESCC, although a decreased risk of ESCC among men and current smokers is suggested, but need to be confirmed in further prospective studies including more cases.
Source: International Journal of Cancer
DOI: 10.1002/ijc.28789
Authors: Raul Zamora‐Ros, Leila Luján‐Barroso, H. B(as) Bueno‐de‐Mesquita, Vincent K. Dik, Heiner Boeing, Annika Steffen, Anne Tjønneland, Anja Olsen, Bodil Hammer Bech, Kim Overvad, Marie‐Christine Boutron‐Ruault, Antoine Racine, Guy Fagherazzi, Tilman Kuhn, Verena Katzke, Antonia Trichopoulou, Pagona Lagiou, Dimitrios Trichopoulos, Rosario Tumino, Salvatore Panico, Paolo Vineis, Sara Grioni, Domenico Palli, Elisabete Weiderpass, Guri Skeie, José María Huerta, María‐José Sánchez, Marcial Argüelles, Pilar Amiano, Eva Ardanaz, Lena Nilsson, Bengt Wallner, Björn Lindkvist, Peter Wallström, Petra H.M. Peeters, Timothy J. Key, Kay‐Thee Khaw, Nicholas J. Wareham, Heinz Freisling, Magdalena Stepien, Pietro Ferrari, Marc J. Gunter, Neil Murphy, Elio Riboli, Carlos A. González
Institutions: Institut d'Investigació Biomédica de Bellvitge, Institut Català d'Oncologia, University Medical Center Utrecht, National Institute for Public Health and the Environment, Imperial College London, German Institute of Human Nutrition, Danish Cancer Society, Aarhus University, Université Paris-Sud, Inserm, Centre de recherche en Epidémiologie et Santé des Populations, German Cancer Research Center, Hellenic Health Foundation, Harvard University, National and Kapodistrian University of Athens, Academy of Athens, Azienda Usl 8 Arezzo, Federico II University Hospital, University of Naples Federico II, Italian institute for Genomic Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Istituto per lo Studio e la Prevenzione Oncologica, Karolinska Institutet, Cancer Registry of Norway, Folkhälsans Forskningscentrum, UiT The Arctic University of Norway, Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública, Andalusian School of Public Health, Gobierno del Principado de Asturias, Basque Government, Biogipuzkoa Health Research Institute, Instituto de Salud Pública de Navarra, Umeå University, University of Gothenburg, Lund University, University of Oxford, Cancer Research UK Oxford Centre, University of Cambridge, Wellcome/MRC Institute of Metabolic Science, MRC Epidemiology Unit, Centre international de recherche sur le cancer
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Funders: American Institute for Cancer Research, Compagnia di San Paolo, Kræftens Bekæmpelse, Deutsches Krebsforschungszentrum, Wellcome Trust, Cancer Research UK, National Institute for Health and Care Research, British Heart Foundation, Food Standards Agency, Stroke Association, European Commission, Institut National de la Santé et de la Recherche Médicale, Bundesministerium für Bildung und Forschung, Cancerfonden, Ligue Contre le Cancer, Ministerio de Ciencia e Innovación, Deutsche Krebshilfe, Institut Gustave-Roussy, Hellenic Health Foundation, Medical Research Council, World Cancer Research Fund
OpenAlex ID: W1893201313