Work

PLC/PRF/5 (Alexander) hepatoma cell line: further characterization and studies of infectivity

Year: 1980
Type: article
Abstract: The Alexander hepatoma cell line, PLC/PRF/5, was studied for evidence of hepatitis B virus markers and alpha-fetoprotein. Only hepatitis B surface antigen and alpha-fetoprotein were detected. Induction experiments with 5-iodo-2'-deoxyuridine and inoculation of chimpanzees with whole cells or tissue culture fluid did not reveal evidence of synthesis of additional hepatitis B virus markers or of production of infectious virus.
Language: English
Subfield: Epidemiology
Field: Medicine
Open Access status: green
OpenAlex ID: W1895325113
FWCI: 1.578
Cites: 21
Cited by: 31
Related to: 10