Work

TYRO3-mediated regulation of MITF: a novel target in melanoma?

Year: 2009

Type: article

Abstract: primary melanoma cells with the B-RAF selective inhibitor PLX4720.The authors found a profound cross-resistance of these cells to drug treatment.The authors then investigated the effect of PLX4720 treatment on MEK resistant primary alleles (AZD6244 binding mutants) and secondary alleles (P124L,

Source: Pigment Cell & Melanoma Research

DOI: 10.1111/j.1755-148x.2009.00649.x

Authors: Udo Rudloff, Yardena Samuels

Language: English

Topic: Melanoma and MAPK Pathways

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $5,000

Funders: National Institutes of Health, National Human Genome Research Institute