Work

Tailored polymeric membranes for Mycobacterium smegmatis porin A (MspA) based biosensors

Year: 2015

Type: article

Abstract: was used as a qualitative tool for understanding protein-membrane interactions in polymer membranes. Polymer compositions with f-ratios close to lipid membranes caused noise behaviour not observed in lipid membranes. However, by modifying the f-ratio using a modular synthetic approach, we were able to design a block copolymer exhibiting noise properties similar to a lipid membrane, albeit with better stability. Thus, by careful optimization, block copolymer membranes can emerge as a robust alternative for protein-pore based nano-biosensors.

Source: Journal of Materials Chemistry B

DOI: 10.1039/c5tb00383k