Work

Viedma ripening: a reliable crystallisation method to reach single chirality

Year: 2015

Type: review

Abstract: Crystallisation processes have evolved to practical methods that allow isolation of an enantiopure product in high yield. Viedma ripening in particular enables access to enantiopure products in a reliable way, simply through grinding of crystals in a solution. This tutorial review covers the basic principles behind asymmetric crystallisation processes, with an emphasis on Viedma ripening, and shows that to date many novel organic molecules can be obtained in enantiopure solid form.

Source: Chemical Society Reviews

DOI: 10.1039/c5cs00196j

Authors: Leyla-Cann Sögütoglu, René R. E. Steendam, Hugo Meekes, Elias Vlieg, Floris P. J. T. Rutjes

Institution: Radboud University Nijmegen

Language: English

Topic: Crystallization and Solubility Studies

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

Open Access status: hybrid

OpenAlex ID: W1909037853

FWCI: 0.617

Cites: 51

Cited by: 234

Related to: 10