Inside Cover: Asymmetric Catalysis on the Nanoscale: The Organocatalytic Approach to Helicenes (Angew. Chem. Int. Ed. 20/2014)
Year: 2014
Type: article
Abstract: The asymmetric synthesis of helicenes by a Fischer indolization catalyzed by a SPINOL-derived phosphoric acid is reported by B. List et al. in their Communication on page 5202 ff. The catalyst is designed for long-range control and bears extended π-surfaces at the 3,3′-position. It creates a chiral nanometer-sized pocket, which enables π–π stacking interactions between the substituents and the reactive intermediate. A variety of (di)azahelicenes were obtained with good to excellent yields and enentioselectivities.
Authors: Lisa Kötzner, Matthew J. Webber, Alberto Martínez, Claudia De Fusco, Benjamin List
Institution: Max-Planck-Institut für Kohlenforschung
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: bronze
OpenAlex ID: W1911413363