Work

Bisphosphonates and jaw osteonecrosis

Year: 2009

Type: article

Abstract: Bisphosphonates have been widely prescribed for treatment of diseases characterized by intense bone resorption. These drugs have also been associated with a serious side effect, avascular osteonecrosis of the jaws. The authors present a literature review on bisphosphonates, focusing on their pharmacological features and their reported association with jaw osteonecrosis. The morbidity and lack of treatment response of this condition are serious facts to be considered when prescribing bisphosphonate therapy. The risk-benefit relationship needs to be seriously analyzed, and the treatment pros and cons should be explained to the patient. If the therapy with bisphosphonate is indicated, rigorous oral health adequacy must be performed and periodic evaluation of oral conditions is mandatory. At this moment, caution in treatment seems to be the best way to approach bisphosphonate users.

Source: LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)

Authors: Márcia Angélica Peter Maahs, Vanessa Paim Nora, Alan A. Azambuja, Karen Cherubini

Institution: Pontifícia Universidade Católica do Rio Grande do Sul

Language: Portuguese

Topic: Bone health and treatments

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W1916852871

FWCI:

Cites: 75

Cited by: 2

Related to: 10