Work

Synthesis of Oxime-Linked Mucin Mimics Containing the Tumor-Related TN and Sialyl TN Antigens

Year: 2001

Type: article

Abstract: [reaction--see text] The synthesis of oxime-linked mucin mimics was accomplished via the incorporation of multiple ketone residues into a peptide followed by reaction with aminooxy sugars corresponding to the tumor-related T(N) and sialyl T(N) (ST(N)) antigens.

Source: Organic Letters

DOI: 10.1021/ol0166247

Authors: Lisa A. Marcaurelle, Youngsook Shin, Scarlett Goon, Carolyn R. Bertozzi

Institutions: Howard Hughes Medical Institute, University of California, Berkeley

Language: English

Topic: Carbohydrate Chemistry and Synthesis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W1918364069