Work

Paired sequence difference in ribosomal RNAs: evolutionary and phylogenetic implications.

Year: 1988

Type: article

Abstract: Ribosomal RNAs have secondary structures that are maintained by internal Watson-Crick pairing. Through analysis of chordate, arthropod, and plant 5S ribosomal RNA sequences, we show that Darwinian selection operates on these nucleotide sequences to maintain functionally important secondary structure. Insect phylogenies based on nucleotide positions involved in pairing and the production of secondary structure are incongruent with those constructed on the basis of positions that are not. Furthermore, phylogeny reconstruction using these nonpairing bases is concordant with other, morphological data.

Source: Molecular Biology and Evolution

DOI: 10.1093/oxfordjournals.molbev.a040480

Authors: W C Wheeler, R L Honeycutt

Institution: Harvard University

Language: English

Topic: RNA and protein synthesis mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funder: National Science Foundation

OpenAlex ID: W1918720391