Relationships between adipokine levels and anthropometric and metabolic variables in overweight and obese women
Year: 2009
Type: article
Study design: Observational Study
Abstract: ABSTRA C T Objective. To analyze the capacity of anthropometric variables to predict the adipokine levels and their relationship with metabolic parameters in overweight and obese women. Methods. Leptin and adiponectin levels were measured in 51 adult overweight or obese women. Data were then correlated with body mass index (BMI), percentage fat mass (%FM), waist circumference (WC), resting metabolic rate (RMR), insulinemia, glycemia and lipid profile. Results. From a simple linear regression model, the mean contribution of BMI, %FM and WC to changes in leptin levels was 36.5%, 33.4% and 23.7%, respectively. No correlation was observed with adiponectin levels, but was noted between leptinemia and both insulin (p < 0.001) and triglyceride levels (p = 0.009). Despite the negative correlation found between RMR and BMI or %FM (p < 0.05), levels of both adipokines showed no correlation with RMR, even when these endocrine variables were adjusted to the assessed anthopometric parameters. Conclusion. BMI and %FM are factors for predicting leptin levels, but not for adiponectinemia in this study population. The negative correlation between BMI or %FM and RMR appears to be independent of adipokine levels.
Institutions: Universidade Feevale, University of Córdoba
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W1919728135