Work

Neonatal seizures: controversies and challenges in translating new therapies from the lab to the isolette

Year: 2012

Type: review

Abstract: Neonatal seizures have unique properties that have proved challenging for both clinicians and basic science researchers. Clinical therapies aimed at neonatal seizures have proven only partially effective and new therapies are slow to develop. This article will discuss neonatal seizures within the framework of the barriers that exist to the development of new therapies, and the challenges inherent in bringing new therapies from the bench to the bedside. With the European Union and USA creating national collaborative project infrastructure, improved collaborative resources should advance clinical research on urgently needed new therapies for this disorder.

Source: European Journal of Neuroscience

DOI: 10.1111/j.1460-9568.2012.08140.x

Authors: Kevin E. Chapman, Yogendra H. Raol, Amy Brooks‐Kayal

Institutions: Children's Hospital Colorado, University of Colorado Anschutz

Language: English

Topic: Epilepsy research and treatment

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: European Commission, National Institute of Neurological Disorders and Stroke, Eunice Kennedy Shriver National Institute of Child Health and Human Development