Work

The dynamics of HDAC activity on memory formation.

Year: 2009

Type: article

Abstract: Histone deacetylases (HDACs) have previously been shown to be critical for the formation of long-term memories. Recent findings now show that a specific HDAC isoform, HDAC2, negatively regulates formation of hippocampus-dependent memory. These recent findings published in Nature highlight potential new therapeutic interventions for the treatment of memory impairments associated with human neurological disorders.

Source: PubMed

Authors: Nicola M Grissom, Farah D Lubin

Institution: University of Alabama at Birmingham

Language: English

Topic: Memory and Neural Mechanisms

Subfield: Cognitive Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of Mental Health

Award: Epigenetic Mechanisms of Gene Regulation in Long-Term Memory Formation