Work

Capacity of Helicobacter pylori to generate ionic gradients at low pH is similar to that of bacteria which grow under strongly acidic conditions

Year: 1996

Type: article

Abstract: Helicobacter pylori colonized the highly acidic human gastric mucosa. At pH 3.0 to 7.0, this bacterium maintained a nearly neutral internal pH. Its membrane potential changed reciprocally with the pH gradient so that a relatively constant proton motive force was maintained. Possible, the capacity to maintain an appropriate transmembrane ionic gradient at a low pH contributes to the pathogenic propensities of this bacterium.

Source: Infection and Immunity

DOI: 10.1128/iai.64.4.1434-1436.1996

Authors: A Matin, E Zychlinsky, M Keyhan, G Sachs

Institutions: Stanford Medicine, Stanford University

Language: English

Topic: Helicobacter pylori-related gastroenterology studies

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funder: National Institute of Diabetes and Digestive and Kidney Diseases