Work

Cyclometalated iridium( iii ) complexes as lysosome-targeted photodynamic anticancer and real-time tracking agents

Year: 2015

Type: article

Abstract: monitoring of therapeutic effect and real-time assessment of treatment outcome. Our work provides a strategy for the construction of highly effective multifunctional subcellular targeted photodynamic anticancer agents through rational structural modification of phosphorescent metal complexes.

Source: Chemical Science

DOI: 10.1039/c5sc01955a

Authors: Liang He, Yi Li, Cai-Ping Tan, Rui-Rong Ye, Mu-He Chen, Jian-Jun Cao, Liang-Nian Ji, Zong-Wan Mao

Institution: Sun Yat-sen University

Language: English

Topic: Photodynamic Therapy Research Studies

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: diamond

Funders: National Natural Science Foundation of China, Ministry of Education of the People's Republic of China, National High-tech Research and Development Program, National Key Research and Development Program of China, Fundamental Research Funds for the Central Universities

Awards: G177376925, G1828425977, G2253746109, G3418245058, G3663125715, G4243412236, G4454147219, G4573084881, G6256989937, 环糊精功能化无机纳米材料的构建及其介导的肿瘤多靶点治疗研究, G8260653709, 靶向组蛋白去乙酰化酶的金属有机铂/铱配合物抗肿瘤活性及机制研究

OpenAlex ID: W1928594450

FWCI: 10.85

Cites: 76

Cited by: 366

Related to: 10