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Anti-inflammatory and anti-nociceptive activities of the ethanolic extract of Annona muricata leaf

Year: 2010

Type: article

Abstract: Ethanolic extract of Annona muricata leaf (AML) was used to investigate its anti-inflammatory and antinociceptive activities by using carrageenan - induced oedema model and acetic acid induced writhing test. AML exhibited significant and dose-dependent anti-inflammatory activity at a dose of 10, 30, 100 and 300 mg/kg when administered orally. It is also demonstrated that the intraperitoneal administration of AML at a dose of 30, 100 and 300 mg/kg produced significant inhibition of abdominal constriction induced with 0.6% (v/v) acetic acid in dose dependent manner. These results indicate that AML exhibits significant anti-inflammatory and antinociceptive effects.

Source: Universiti Putra Malaysia Institutional Repository (Universiti Putra Malaysia)

Authors: A. H. Roslida, C. E. Tay, A. Zuraini, Paul Chan

Language: English

Topic: Traditional and Medicinal Uses of Annonaceae

Subfield: Biochemistry

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W1930816615

FWCI: 0.391

Cites:

Cited by: 18

Related to: 10