Work

Biological activities of toxins A and B of Clostridium difficile

Year: 1982
Type: article
Abstract: Examination of the biological activities of the two known toxins of Clostridium difficile revealed that one of the toxins (toxin A) elicited a hemorrhagic fluid response in rabbit intestinal loops and a positive fluid response in infant mice. The other toxin (toxin B) did not produce a significant fluid response in either model, although the toxin was more lethal in infant mice. Both toxins elicited erythematous and hemorrhagic skin reactions and increased vascular permeability in rabbit skin.
Language: English
Field: Medicine
Open Access status: bronze
OpenAlex ID: W1931706359
FWCI: 12.58
Cites: 22
Cited by: 259
Related to: 9