Work

Membrane Association of Conjugally Transferred Deoxyribonucleic Acid in Escherichia coli Minicells

Year: 1971

Type: article

Abstract: The conjugally acquired deoxyribonucleic acid (DNA) of small, anucleate cells ("minicells") of a mutant strain of Escherichia coli K-12 was found to be predominantly associated with the bacterial membrane. Evidence from X-irradiation studies in vivo shows that there is no decrease in DNA-membrane association under conditions which reduce the DNA to one-sixth its original size and suggests the possibility of multiple DNA-membrane association sites. Preliminary enzymatic studies indicate the involvement of protein, DNA, and lipids in the membrane association of the DNA.

Source: Journal of Bacteriology

DOI: 10.1128/jb.106.2.626-633.1971

Authors: Fred W. Shull, Joe A. Fralick, Lewis P. Stratton, William D. Fisher

Institutions: Oak Ridge National Laboratory, University of Tennessee at Knoxville, Furman University

Language: English

Topic: Bacterial Genetics and Biotechnology

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W1933794991

FWCI: 5.512

Cites: 35

Cited by: 23

Related to: 10