Work

The Solubility of Amino Acids, Diglycine, and Triglycine in Aqueous Guanidine Hydrochloride Solutions

Year: 1970

Type: article

Abstract: The solubilities of amino acids, diglycine, and triglycine have been measured in water and 1 m to 6 m guanidine hydrochloride solutions. Free energies of transfer of amino acid side chains and backbone peptide units from water to guanidine hydrochloride solutions have been calculated from these data. The results show similarity between the patterns of solubilizing effects of guanidine hydrochloride and urea, although guanidine hydrochloride is 2 to 3 times more effective than urea at the same concentrations.

Source: Journal of Biological Chemistry

DOI: 10.1016/s0021-9258(19)77141-5

Authors: Yasuhiko Nozaki, Charles Tanford

Institution: Duke Medical Center

Language: English

Topic: Chemical and Physical Properties in Aqueous Solutions

Subfield: Filtration and Separation

Field: Chemical Engineering

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $3,430

OpenAlex ID: W1935984619

FWCI: 12.41

Cites: 16

Cited by: 350

Related to: 10