Work

Structural basis for processivity and antiviral drug toxicity in human mitochondrial DNA replicase

Year: 2015

Type: article

Source: The EMBO Journal

DOI: 10.15252/embj.201591520

Authors: Michal R Szymanski, Vladmir B Kuznetsov, Christie Shumate, Qingchao Meng, Young‐Sam Lee, Gayatri Patel, Smita Patel, Y Whitney Yin

Institutions: The University of Texas Medical Branch at Galveston, Rutgers, The State University of New Jersey

Language: English

Topic: Enzyme Structure and Function

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Welch Foundation, National Institutes of Health, National Institute of General Medical Sciences, Argonne National Laboratory, Lawrence Berkeley National Laboratory

Awards: G1409003578, Dissecting dual function of Pol gamma in mtDNA replication and oxidative damage r, G3375417104, G5589841258, Studies of toxicities of HIV RT inhibitors to human mitochondrial DNA polymerase, G7267144468, Mechanistic Studies of Hexameric Helicases

OpenAlex ID: W1939528983

FWCI: 2.433

Cites: 48

Cited by: 68

Related to: 10